Original Articles Publications

Iron-Catalyzed Chemoselective Cross-Coupling of Primary and Secondary Alkyl Halides with Arylzinc Reagents

Date:2005-06-14

M. Nakamura*, S. Ito, K. Matsuo, E. Nakamura*
Synlett 2005, 1794–1798.  DOI: 10.1055/s-2005-871541

Abstract: Functional-group-compatible cross-coupling reaction of alkyl halides with arylzinc reagents takes place under iron catalysis in the presence of TMEDA, producing a variety of aromatic ­compounds in good to excellent yield. The pronounced effect of a magnesium salt was found to be the key to the promotion of the iron-catalyzed coupling reaction.

-Original Articles, Publications

Copyright© Ito Group , 2018 All Rights Reserved.